Objective Discussion on type 2 diabetes mellitus (DM2) of the clinical characteristics of patients with colorectal cancer, to understand the effect of hyperglycemia on colorectal cancer.Methods A retrospective analysis of 31 patients with DM2 colorectal cancer clinical data (experimental group) and 60 cases of colorectal cancer patients without diabetes (control group), analysis of colorectal cancer patients with DM2 hypertension, clinical stage and metastasis characteristics.Results No diabetes group with hypertension in 16.7%; colorectal cancer with DM2 group was 29.0%, there was no significant difference; Diabetes without lymph node and organ metastasis rate was 21.7%, colorectal cancer patients with DM2 group was 46.2%, there was significant difference (P=0.02); no significant difference between the effects of hyperglycemia in patients with colorectal cancer gender, TNM stage.Conclusion Patients with DM2 colorectal cancer patients with colorectal cancer patients are more prone to metastasis, DM2 increased the risk of rectal cancer metastasis.%目的：探讨合并2型糖尿病的结直肠癌患者的临床特点，了解高血糖对结直肠癌的影响。方法选取确诊10年以上糖尿病史的结直肠癌患者为实验组（n=31）和结直肠癌无糖尿病患者为对照组（n=60），分析结直肠癌合并2型糖尿病的高血压情况、临床分期及远处转移的特点。结果无糖尿病组伴有高血压者16.7%；结直肠癌伴2型糖尿病组为29.0%，差异无统计学意义；无糖尿病组淋巴结或器官转移率为21.7%，合并2型糖尿病的结直肠癌组为45.2%，差异有统计学意义（P=0.02）；高血糖对于结直肠癌患者的性别、TNM分期的影响比较，差异无统计学意义。结论伴有2型糖尿病的结直肠癌患者较单纯结直肠癌患者更易发生转移，2型糖尿病增加了结直肠癌转移的危险性。
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