Optimal Formula of Angelica sinensis Ameliorates Memory Deficits in β-amyloid Protein-induced Alzheimer's Disease Rat Model

Hu-ping WANG; Hong-yan WU; Chun-lin MA; Qing-tao ZENG; Kai-min ZHU; Shu-mei CUI; Hai-long LI; Guo-tai WU; Zhi-wei WU; Jian-zheng HE

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Optimal Formula of Angelica sinensis Ameliorates Memory Deficits in β-amyloid Protein-induced Alzheimer's Disease Rat Model

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Objective:Angelica(A.)sinensis is used as a traditional medical herb for the treatment of neurodegeneration,aging,and inflammation in Asia.A.sinensis optimal formula(AOF)is the best combination in A.sinensis that has been screened to rescue the cognitive ability in P-amyloid peptide(Ap25-35)-treated Alzheimer’s disease(AD)rats.The objective of this study was to investigate the effect of AOF on the learning and memory of AD rats as well as to explore the underlying mechanisms.

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《当代医学科学(英文)》 |2022年第1期|39-47|共9页
作者
Hu-ping WANG; Hong-yan WU; Chun-lin MA; Qing-tao ZENG; Kai-min ZHU; Shu-mei CUI; Hai-long LI; Guo-tai WU; Zhi-wei WU; Jian-zheng HE;
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作者单位

Basic Medicine College University of Chinese Medicine 730000;

Clinical Medicine College University of Chinese Medicine 730000;

Pharmacy College University of Chinese Medicine 730000;

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原文格式 PDF
正文语种 chi
中图分类神经病学与精神病学;
关键词
optimal formula of Angelica sinensis; Alzheimer's disease; amyloid P aggregation; oxidative stress; NEUROINFLAMMATION;

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Optimal Formula of Angelica sinensis Ameliorates Memory Deficits in β-amyloid Protein-induced Alzheimer's Disease Rat Model

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