The effects of transcranial direct current stimulation on gait in patients with Parkinson’s disease:a systematic review

Fateme Pol; Mohammad Ali Salehinejad; Hamzeh Baharlouei; Michael A.Nitsche

首页> 中文期刊> 《转化神经变性病(英文)》 >The effects of transcranial direct current stimulation on gait in patients with Parkinson’s disease:a systematic review

The effects of transcranial direct current stimulation on gait in patients with Parkinson’s disease:a systematic review

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相关主题

摘要

Background:Gait problems are an important symptom in Parkinson’s disease(PD),a progressive neurodegenerative disease.Transcranial direct current stimulation(tDCS)is a neuromodulatory intervention that can modulate cortical excitability of the gait-related regions.Despite an increasing number of gait-related tDCS studies in PD,the efficacy of this technique for improving gait has not been systematically investigated yet.Here,we aimed to systematically explore the effects of tDCS on gait in PD,based on available experimental studies.Methods:Using the PRISMA(Preferred Reporting Items for Systematic Reviews and Meta-Analyses)approach,PubMed,Web of Science,Scopus,and PEDro databases were searched for randomized clinical trials assessing the effect of tDCS on gait in patients with PD.Results:Eighteen studies were included in this systematic review.Overall,tDCS targeting the motor cortex and supplementary motor area bilaterally seems to be promising for gait rehabilitation in PD.Studies of tDCS targeting the dorosolateral prefrontal cortex or cerebellum showed more heterogeneous results.More studies are needed to systematically compare the efficacy of different tDCS protocols,including protocols applying tDCS alone and/or in combination with conventional gait rehabilitation treatment in PD.Conclusions:tDCS is a promising intervention approach to improving gait in PD.Anodal tDCS over the motor areas has shown a positive effect on gait,but stimulation of other areas is less promising.However,the heterogeneities of methods and results have made it difficult to draw firm conclusions.Therefore,systematic explorations of tDCS protocols are required to optimize the efficacy.

著录项

来源
《转化神经变性病(英文)》 |2021年第2期|P.275-293|共19页
作者
Fateme Pol; Mohammad Ali Salehinejad; Hamzeh Baharlouei; Michael A.Nitsche;
展开▼
作者单位

Musculoskeletal Research Center Isfahan University of Medical Sciences Isfahan Iran;

Department of Psychology and Neurosciences Leibniz Research Centre for Working Environment and Human Factors Dortmund Germany;

Musculoskeletal Research Center Isfahan University of Medical Sciences Isfahan Iran;

Department of Psychology and Neurosciences Leibniz Research Centre for Working Environment and Human Factors Dortmund GermanyDepartment of Neurology University Medical Hospital Bergmannsheil Bochum Germany;

展开▼
原文格式 PDF
正文语种 chi
中图分类铁路通信、信号;
关键词
Transcranial direct current stimulation; Gait; Parkinson’s disease;

The effects of transcranial direct current stimulation on gait in patients with Parkinson’s disease:a systematic review

摘要

著录项

相关主题

期刊订阅