Intranasal rapamycin ameliorates Alzheimerlike cognitive decline in a mouse model of Down syndrome

著录项

• 来源
  《转化神经变性病(英文)》 |2018年第1期|P.285-306|共22页
• 作者

  Antonella Tramutola; Chiara Lanzillotta; Eugenio Barone; Andrea Arena; Ilaria Zuliani; Luciana Mosca; Carla Blarzino; D.Allan Butterfield; Marzia Perluigi; Fabio Di Domenico;

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• 作者单位

  Department of Biochemical Sciences Sapienza University of Rome P.le Aldo Moro 5 00185 Rome Italy;

  Department of Biochemical Sciences Sapienza University of Rome P.le Aldo Moro 5 00185 Rome Italy;

  Department of Biochemical Sciences Sapienza University of Rome P.le Aldo Moro 5 00185 Rome ItalyUniversidad Autònoma de Chile Instituto de Ciencias Biomédicas Facultad de alud Avenida Pedro de Valdivia 425 Providencia Santiago Chile;

  Department of Biochemical Sciences Sapienza University of Rome P.le Aldo Moro 5 00185 Rome Italy;

  Department of Biochemical Sciences Sapienza University of Rome P.le Aldo Moro 5 00185 Rome Italy;

  Department of Biochemical Sciences Sapienza University of Rome P.le Aldo Moro 5 00185 Rome Italy;

  Department of Biochemical Sciences Sapienza University of Rome P.le Aldo Moro 5 00185 Rome Italy;

  Department of Chemistry and Sanders-Brown Center on Aging University of Kentucky Lexington KY 40506-0055 USA;

  Department of Biochemical Sciences Sapienza University of Rome P.le Aldo Moro 5 00185 Rome Italy;

  Department of Biochemical Sciences Sapienza University of Rome P.le Aldo Moro 5 00185 Rome Italy;

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• 原文格式 PDF
• 正文语种 chi
• 中图分类 肿瘤学;
• 关键词

  mTOR; Autophagy; Rapamycin; Down syndrome; Alzheimer disease; APP; Tau; Oxidative stress;