A Human T Lymphotropic Virus Type 1 Carrier Coinfected with iMycobacterium intracellulare/iand iPneumocystis jirovecii/iwith a Characteristic Compositional Change of Bone Marrow Cells

Sayaka Uda; Shinsuke Shiotsu; Ayaka Omura; Ryosuke Hamashima; Akihiro Yoshimura; Naoko Kurisu; Tomoya Sagawa; Koichi Hasegawa; Tatsuya Yuba; Chieko Takumi; Seiko Ono; Noriya Hiraoka; Noriya Hiraoka

首页> 中文期刊> 《呼吸病期刊（英文）》 >A Human T Lymphotropic Virus Type 1 Carrier Coinfected with iMycobacterium intracellulare/iand iPneumocystis jirovecii/iwith a Characteristic Compositional Change of Bone Marrow Cells

A Human T Lymphotropic Virus Type 1 Carrier Coinfected with iMycobacterium intracellulare/iand iPneumocystis jirovecii/iwith a Characteristic Compositional Change of Bone Marrow Cells

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Human T lymphotropic virus type 1 (HTLV-1) is endemic in the southern part of Japan. Infection of the virus can cause adult T cell leukemia/lymphoma (ATL), while most infected individuals remain in a carrier state for a long period of time. Although rare cases of carriers, like ATL patients, who developed opportunistic infections, have been reported, hematological changes of carriers who are prone to opportunistic infections have not been well defined. Here, we present a case of an HTLV-1 carrier who developed Mycobacterium intracellulare infection and Pneumocystis jirovecii pneumonia (PcP) simultaneously. Flow cytometric analysis of bone marrow cells revealed an aberrant compositional change similar to that in ATL patients. This suggests the presence of a pre-ATL state prior to the development of ATL, which is notable in terms of underlying cellular immunodeficiency.

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来源
《呼吸病期刊（英文）》 |2017年第3期|110-116|共7页
作者
Sayaka Uda; Shinsuke Shiotsu; Ayaka Omura; Ryosuke Hamashima; Akihiro Yoshimura; Naoko Kurisu; Tomoya Sagawa; Koichi Hasegawa; Tatsuya Yuba; Chieko Takumi; Seiko Ono; Noriya Hiraoka; Noriya Hiraoka;
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作者单位

Department of Respiratory Medicine;

Japanese Red Cross Kyoto Daiichi Hospital;

Kyoto;

Japan;

Department of Respiratory Medicine;

Graduate School of Medicine;

Kyoto University;

Kyoto;

Japan;

Department of Infection Control and Prevention;

Japanese Red Cross Kyoto Daiichi Hospital;

Kyoto;

Japan;

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原文格式 PDF
正文语种 chi
中图分类内科学;
关键词
Human; T; Lymphotropic; Virus; Type; 1; Carrier; Immunodeficiency; Pneumocystis; jirovecii;

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A Human T Lymphotropic Virus Type 1 Carrier Coinfected with iMycobacterium intracellulare/iand iPneumocystis jirovecii/iwith a Characteristic Compositional Change of Bone Marrow Cells

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