目的 探讨鼻内镜下经咽鼓管鼓室联合用药辅助治疗突发性耳聋伴糖尿病的效果.方法 随机抽取2015年1月-2018年5月在该院住院治疗的64例(68耳)SSNHL伴2型胰岛素依赖型糖尿病患者,发病后1 d～1周,治疗组32例(34耳),对照组32例(34耳).对照组患者接受常规全身用药治疗,治疗组患者接受常规全身用药配合经咽鼓管咽口鼓室内注药治疗,然后统计分析两组患者的临床疗效、PTA.结果 治疗组患者治疗的总有效率88.2％(30/34)显著高于对照组67.6％(23/34),差异有统计学意义(P＜0.05).和治疗前相比,两组患者治疗后的PTA均显著降低,差异有统计学意义(P＜0.05);治疗后和对照组相比,治疗组患者的PTA显著降低,差异有统计学意义(P＜0.05),但治疗前两组患者的PTA之间的差异无统计学意义(P＞0.05).治疗组患者治疗前后PTA降低幅度显著大于对照组,差异有统计学意义(P＜0.05).治疗组治疗前后的空腹血糖之间的差异无统计学意义(P＞0.05).结论 鼻内镜下经咽鼓管鼓室联合用药辅助治疗突发性耳聋伴糖尿病的效果好.%Objective To investigate the effect of combined use of eustachian tube and tympanic cavity in the treatment of sudden deafness with diabetes under nasal endoscopy. Methods 64 cases (68 ears) SSNHL patients with type 2 insulin-dependent diabetes mellitus admitted to our department from January 2015 to May 2018 were randomly selected. One day to one week after onset, 32 patients in the treatment group (34 ears), 32 patients in the control group (34 ears). The patients in the control group received conventional systemic medication. The patients in the treatment group received conventional systemic medication combined with intra-abdominal injection in the eustachian tube, and then statistically analyzed the clinical efficacy and PTA of the two groups. Results The total effective rate of treatment in the treatment group was 88.2％ (30/34), which was significantly higher than that in the control group (67.6％, 23/34), the different was statistically significant (P＜0.05).Compared with before treatment, the PTA of the two groups was significantly decreased after treatment, the different was statistically significant (P＜0.05). After treatment, the PTA of the treatment group was significantly lower than that of the control group, the different was statistically significant (P＜0.05), but the two groups before treatment between PTA was not statitically significant difference (P＞0.05). The decrease of PTA in the treatment group before and after treatment was significantly greater than that in the control group, the different was statistically significant (P＜0.05). There was no statitically significant difference in fasting blood glucose between the treatment group before and after treatment (P＞0.05). Conclusion The combination of eustachian tube and tympanic cavity in the treatment of sudden deafness with diabetes is better.
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