Emerging Trends for Microbiome Analysis: From Single-Cell Functional Imaging to Microbiome Big Data

Jian Xu; Bo Ma; Xiaoquan Su; Shi Huang; Xin Xu; Xuedong Zhou; Wei E. Huang; Rob Knight

首页> 中文期刊> 《工程（英文）》 >Emerging Trends for Microbiome Analysis: From Single-Cell Functional Imaging to Microbiome Big Data

Emerging Trends for Microbiome Analysis: From Single-Cell Functional Imaging to Microbiome Big Data

开具论文收录证明 >>

期刊封面封底目录下载 >>

文献代查 >>

页面导航

摘要
著录项
相关主题

摘要

Method development has always been and will continue to be a core driving force of microbiome science.In this perspective, we argue that in the next decade, method development in microbiome analysis will be driven by three key changes in both ways of thinking and technological platforms:(1) a shift from dissecting microbiota structure by sequencing to tracking microbiota state, function, and intercellular interaction via imaging;(2) a shift from interrogating a consortium or population of cells to probing individual cells;and(3) a shift from microbiome data analysis to microbiome data science. Some of the recent methoddevelopment efforts by Chinese microbiome scientists and their international collaborators that underlie these technological trends are highlighted here. It is our belief that the China Microbiome Initiative has the opportunity to deliver outstanding 'Made-in-China' tools to the international research community, by building an ambitious, competitive, and collaborative program at the forefront of method development for microbiome science.

著录项

来源
《工程（英文）》 |2017年第001期|P.66-70|共11页
作者
Jian Xu; Bo Ma; Xiaoquan Su; Shi Huang; Xin Xu; Xuedong Zhou; Wei E. Huang; Rob Knight;
展开▼
作者单位

[1]Single-Cel Center, CAS Key Laboratory of Biofuels,Shandong Key Laboratory of Energy Genetics, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong 266101, China,University of Chinese Academy of Sciences, Beijing 100049, China;

[1]Single-Cel Center, CAS Key Laboratory of Biofuels,Shandong Key Laboratory of Energy Genetics, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong 266101, China,University of Chinese Academy of Sciences, Beijing 100049, China;

[1]Single-Cel Center, CAS Key Laboratory of Biofuels,Shandong Key Laboratory of Energy Genetics, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong 266101, China,University of Chinese Academy of Sciences, Beijing 100049, China;

[1]Single-Cel Center, CAS Key Laboratory of Biofuels,Shandong Key Laboratory of Energy Genetics, Qingdao Institute of BioEnergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, Shandong 266101, China,University of Chinese Academy of Sciences, Beijing 100049, China;

[2]State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China;

[2]State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China;

[3]Department of Engineering Science, University of Oxford, Oxford OX13PJ, UK;

[4]Center for Microbiome Innovation, Department of Pediatrics, Department of Computer Science and Engineering, University of California, San Diego, CA 92093, USA;

展开▼
原文格式 PDF
正文语种 CHI
中图分类肿瘤学;
关键词

Emerging Trends for Microbiome Analysis: From Single-Cell Functional Imaging to Microbiome Big Data

摘要

著录项

相关主题

期刊订阅