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首页> 中文期刊> 《工程（英文）》 >One-Step Preparation of Green Fabric for Continuous Antibacterial Applications

One-Step Preparation of Green Fabric for Continuous Antibacterial Applications

         
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摘要

Polypropylene(PP)scaffolds are the most commonly used biomedical scaffolds despite their disadvan-tages,which include problems with adhesion,infection,and inflammatory responses.Here,we report on the successful development of a facile one-step method to fabricate a series of novel triclosan poly-dopamine polypropylene(TPP)composite scaffolds and thereby effectively improve the biocompatibility and long-term antibacterial properties of PP scaffolds.The antibacterial triclosan can effectively interact with dopamine during biocompatible polydopamine formation on the PP scaffold by one-step green fab-rication.Thanks to the sustained release of triclosan from the biocompatible polydopamine coating,a 5mm×5mm sample of TPP-coated scaffold made with a triclosan concentration of 8 mg-mL^(-1)(referredto herein as TPP-8)exhibited a continuous antibacterial effect against both Escherichia coli(E.coli)and Staphylococcus aureus(S.aureus)for more than 15d,at maximum antibacterial volumes of 2 and 5mL,respectively.Our study establishes a new direction for facile long-term antibacterial studies for medical applications.

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  • 来源
    《工程（英文）》 |2021年第003期|326-333|共8页
  • 作者

    Rongkang Huang; Chuangkun Li; Ming Li; Hui Wang; Xingcai Zhang; Minghui Hu; Weiwen Liang; Juanjuan Zheng; Yang Du; Yanhuan Lin; Huaiming Wang; Wentai Guo; Zhantao Zeng;

  • 作者单位

    Department of Colorectal Surgery The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    Department of Colorectal Surgery The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    Department of Surgery Dongguan Third Peoples' Hospital Dongguan 523000 China;

    Department of Colorectal Surgery The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    John A.Paulson School of Engineering and Applied Sciences Harvard University Cambridge MA 02138 USA;

    Department of Colorectal Surgery The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    Department of Colorectal Surgery The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    John A.Paulson School of Engineering and Applied Sciences Harvard University Cambridge MA 02138 USA;

    Materials Science Institute PCFM Lab and GDHPRC Lab School of Chemistry Sun Yat-sen University Guangzhou 510275 China;

    Materials Science Institute PCFM Lab and GDHPRC Lab School of Chemistry Sun Yat-sen University Guangzhou 510275 China;

    Department of Colorectal Surgery The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    Department of Colorectal Surgery The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    Department of Colorectal Surgery The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

    Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases The Sixth Affiliated Hospital of Sun Yat-sen University Guangzhou 510655 China;

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  • 正文语种 eng
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