Nanotechnology and Nanomedicine: A Promising Avenue for Lung Cancer Diagnosis and Therapy

Wei Yin; Feng Pan; Junjie Zhu; Junwu Xu; Diego Gonzalez-Rivas; Meinoshin Okumura; Zhiyong Tang; Yang Yang

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Nanotechnology and Nanomedicine: A Promising Avenue for Lung Cancer Diagnosis and Therapy

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Lung cancer is a leading cause of cancer-related death worldwide,with a very poor overall five-year survival rate.The intrinsic limitations associated with the conventional diagnosis and therapeutic strategies used for lung cancer have motivated the development of nanotechnology and nanomedicine approaches,in order to improve early diagnosis rate and develop more effective and safer therapeutic options for lung cancer.Cancer nanomedicines aim to individualize drug delivery,diagnosis,and therapy by tailoring them to each patient’s unique physiology and pathological features—on both the genomic and proteomic levels—and have attracted widespread attention in this field.Despite the successful application of nanomedicine techniques in lung cancer research,the clinical translation of nanomedicine approaches remains challenging due to the limited understanding of the interactions that occur between nanotechnology and biology,and the challenges posed by the toxicology,pharmacology,immunology,and largescale manufacturing of nanoparticles.In this review,we highlight the progress and opportunities associated with nanomedicine use for lung cancer treatment and discuss the prospects of this field,together with the challenges associated with clinical translation.

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《工程（英文）》 |2021年第11期|1577-1585|共9页
作者
Wei Yin; Feng Pan; Junjie Zhu; Junwu Xu; Diego Gonzalez-Rivas; Meinoshin Okumura; Zhiyong Tang; Yang Yang;
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作者单位

Key Laboratory of Oral Biomedical Engineering(Wuhan University);

Ministry of Education;

Hospital of Stomatology;

School of Stomatology;

Wuhan University;

Wuhan 430079;

China;

Department of Biomedical Data Science;

Geisel School of Medicine;

Dartmouth College;

Hanover;

NH 03756;

USA;

Department of Thoracic Surgery;

Shanghai Pulmonary Hospital;

School of Medicine;

Tongji University;

Shanghai 200433;

China;

Tus-Medical Health Technology Investment(Jiaxing)Co.;

Ltd.;

Jiaxing 314033;

China;

Minimally Invasive Thoracic Surgery Unit(UCTMI);

Hospital San Rafael;

Coruña 15006;

Spain;

Osaka Toneyama Medical Center;

Osaka 560-8552;

Japan;

CAS Key Laboratory of Nanosystem and Hierarchical Fabrication;

National Center for Nanoscience and Technology;

Beijing 100190;

China;

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原文格式 PDF
正文语种 chi
中图分类肿瘤学;
关键词
Nanomedicine; Lung cancer; Diagnosis; Therapy;

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1. A triple-combination nanotechnology platform based on multifunctional RNA hydrogel for lung cancer therapy [J] . Junwei Li ,Dandan Yuan ,Xiangjiang Zheng . 中国科学 . 2020,第004期
2. Developing new cancer nanomedicines by combination ancient traditional Chinese medicine effective ingredients and advanced nanotechnology [J] . Sheng-Nan Huang ,Xia-Li Zhu ,Hong Zhu . TMR肿瘤 . 2021,第002期
3. BIO TECHNOLOGY AND BIORESOURCES IN MEDICAL RESEARCH: NEW TARGETS FOR THE DIAGNOSIS AND TREATMENT OF CANCER [C] . . 生物技术及产业化国际论坛 . 2002
4. Developing Nanomedicine Approaches:Design,Synthesis,and Evaluation of New Nanomaterials for Cancer Therapy [A] . Atheer Hameid Odda . 2019

Nanotechnology and Nanomedicine: A Promising Avenue for Lung Cancer Diagnosis and Therapy

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