目的:了解河南中医药大学第一附属医院(以下简称"我院")门诊药房口服抗高血压药应用情况,为临床合理用药提供依据.方法:采用金额排序和限定日剂量分析方法,对2013—2016年我院门诊药房口服抗高血压药的品种、销售金额、用药频度和限定日费用等进行统计分析.结果:2013—2016年我院门诊药房口服抗高血压药的销售金额总体呈增长趋势,其中钙通道阻滞剂(calcium channel blocker,CCB)、血管紧张素Ⅱ受体阻断剂(angiotensinⅡreceptor blocker,ARB)的销售金额排序居前2位,且其销售金额占比均>30％;DDDs排序无变化,由高至低依次为CCB、ARB、血管紧张素转换酶抑制剂(angiotensin converting enzyme inhibitor,ACEI)、复方制剂、β受体阻断剂和利尿剂,其中,CCB、ARB和ACEI的DDDs合计占比>80％.结论:我院门诊药房口服抗高血压药的销售金额和DDDs总体呈增长趋势,临床多优先选择CCB、ARB和ACEI,并倾向选择长效制剂,而固定的复方制剂尚未得到广泛应用.%OBJECTIVE: To investigate the application of oral antihypertensive agents in outpatient pharmacy of the First Affiliated Hospital of Henan University of Traditional Chinese Medicine ( hereinafter referred to as "our hospital") , so as to provide references for clinical rational drug application .METHODS:Amount ranking and defined daily dose (DDDs) were adopted to analyze the categories, consumption sums, DDDs and defined daily cost (DDC) of oral antihypertensive agents in outpatient pharmacy in our hospital during 2013-2016.RESULTS:The consumption sum of oral antihypertensive agents in outpatient pharmacy in our hospital during 2013-2016 was in an increasing trend, of the consumption sums of calcium channel blocker ( CCB ) and angiotensin Ⅱ receptor blocker ( ARB ) ranked the top 2 , both accounted for over 30％ of the total consumption sum; the sequence of DDDs remained from high to low were respectively CCB, ARB, angiotensin converting enzyme inhibitor (ACEI), compound preparations,β-receptor blocking and hydragogue , the DDDs of CCB , ARB and ACEI accounted for over 80％ of the total DDDs. CONCLUSIONS: The consumption sum and DDDs of oral antihypertensive agents in outpatient pharmacy in our hospital were in an overall increasing trend , CCB , ARB and ACEI are more prior in clinics , long-time preparations are more tend to be chosen , however , fixed compound preparations are not widely applied yet .
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