首页> 中文期刊> 《中国医院用药评价与分析》 >金水宝胶囊联合布地奈德福莫特罗粉吸入剂治疗支气管哮喘的疗效观察

金水宝胶囊联合布地奈德福莫特罗粉吸入剂治疗支气管哮喘的疗效观察

         

摘要

OBJECTIVE:To probe into the clinical efficacy and safety of Jinshuibao capsules combined with budesonide and formoterol fumarate powder for inhalation .METHODS:92 patients with bronchial asthma admitted into Shandong Zouping County Central Hospital from Feb .2015 to Aug.2016 were selected to be divided into observation group and control group via the random number table , with 46 cases in each .The control group were given symptomatic treatment and budesonide and formoterol fumarate powder for inhalation ; while the control group were treated with Jinshuibao capsules based on the control group .The treatment course was 1 month.The clinical efficacy , lung function and blood gas index level and adverse reactions were observed in two group of patients .RESULTS: Before treatment , there was no significant difference in ACT score between two groups before ( P>0.05) .After treatment , the ACT score in observation group was ( 20.18 ±2.03 ) scores , significantly lower than that of the control group [ ( 23.74 ±1.95 ) scores], with statistically significant difference (P 0.05);治疗后,观察组患者哮喘控制测试表评分为(20.18±2.03)分,明显低于对照组的(23.74±1.95)分,差异有统计学意义(P<0.05).治疗后,观察组患者1 s用力呼气容积、1 s用力呼气容积占用力肺活量百分比、呼吸峰流速、动脉血氧分压水平明显高于对照组,差异均有统计意义(P<0.05).观察组患者不良反应发生率为8.70%(4/46),明显低于对照组的26.09%(12/46),差异有统计学意义(P<0.05).结论:金水宝胶囊联合布地奈德福莫特罗粉吸入剂治疗支气管哮喘的疗效显著,可有效改善患者肺功能和血气指标,不良反应较少.

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