目的:了解常熟市第二人民医院(以下简称"该院")抗糖尿病药应用情况,为临床合理用药提供参考.方法:采用回顾性方法,参照世界卫生组织推荐的限定日剂量法,对2014-2016年该院抗糖尿病药的销售金额及其年增长率、构成比,用药频度(defined daily dose system,DDDs)和限定日费用等指标进行评价与分析.结果:2014-2016年该院抗糖尿病药销售金额分别为1 157.59、1 204.00、1 225.81万元,呈逐年增长趋势,2015年比2014年增长了4.01%、2016年比2015年增长了1.81%,其占西药总销售金额的比例变化不大.3年来,销售金额排序居第1、2位的分别为胰岛素类似物、磺酰脲类药物,DDDs排序居第1、2位的分别为双胍类药物、磺酰脲类药物;销售金额排序居前3位的药品依次为重组甘精胰岛素注射液、门冬胰岛素30注射液和阿卡波糖片,销售金额排序居前10位药品的销售金额累计占抗糖尿病药销售金额的比例>80%;DDDs排序居前3位的药品依次为二甲双胍(缓释)片、吡格列酮片和格列齐特缓释片,DDDs排序居前10位药品的DDDs累计占抗糖尿病药DDDs的比例>85%.结论:该院抗糖尿病药的使用基本合理,符合目前抗糖尿病药使用规律和趋势.但仍应加强对糖尿病患者的宣传教育,实施个体化给药.%OBJECTIVE:To investigation the application of antidiabetic in Changsu No.2 People`s Hospital(hereinafter referred to as "the hospital") during 2014-2016, so as to provide reference for the clinical rational drug application. METHODS:By retrospective method, evaluation and analysis were conducted on the application data of antidiabetic in terms of consumption sum and its annual growth rate, constituent ratio, defined daily dose system(DDDs) and defined daily cost(DDC) during 2014-2016 according to defined daily dose recommended by WHO. RESULTS:The consumption sum of antidiabetic during 2014-2016 were in an increasing trend, respectively 11.575 9 million yuan, 12.040 0 million yuan and 12.258 1 million yuan; and compared with 2014, the consumption sum of 2015 increased by 4.01%; compared with 2015, the consumption sum of 2016 increased by 1.81%; yet its consumption sum versus the total consumption sum of western medicine had few changes. For three years, the top two antidiabetic ranked by consumption sum were respectively insulin analogue and sulfonylurea, while ranked by DDDs were respectively biguanide and sulfonylurea. The top three drugs ranked by consumption sum were respectively recombinant insulin glargine injection, insulin aspart 30 injection and Acarbose tablets. The ratio of consumption sum of the top ten drugs versus the total consumption sum of antidiabetic was >80%. The top three drugs ranked by DDDs were respectively Metformin (extended-release) tablets, Pioglitazone hydrochloride tablets and Gliclazide sustained-release tablets, the ratio of the top ten drugs versus the total consumption sum of antidiabetic was >85%. CONCLUSIONS:The application of antidiabetic is basically rational in the hospital, in accordance with the regulation and tendency of present application of antidiabetic. It is still necessary to strengthen the publicity and education on diaberic and implement personalized medicine.
展开▼
