首页> 中文期刊> 《中国医院用药评价与分析》 >中药经胃管注入及保留灌肠联合奥曲肽治疗大肠梗阻的疗效观察

中药经胃管注入及保留灌肠联合奥曲肽治疗大肠梗阻的疗效观察

         

摘要

OBJECTIVE:To probe into the clinical efficacy of traditional Chinese medicine for gastric tube injection and retention enema combined with octreotide in treatment of large bowel obstruction(LBO). METHODS:94 patients with LBO admitted into Dongxiang Traditional Chinese Medicine Hospital from Jan. 2014 to Dec. 2016 were collected and divided into control group and observation group via random number table, with 47 cases in each group. The control group was given octreotide, while the observation group was treated with traditional Chinese medicine for gastric tube injection and retention enema combined with octreotide, the therapeutic effects of two groups were compared. RESULTS:The average disappearance time of symptoms, average recovery time of bowel sound, average venting time of anus and average hospital stays of observation group were respectively (5.07±1.91),(2.61±0.99),(2.88±1.29) and (10.15±3.20) days, which was significantly shorter than those of the control group [(6.90±1.73),(3.87±1.25),(3.74±1.36) and (12.83±5.46) days], with statistically significant differences (P<0.05); the total effective rate of observation group (95.74%, 45/47) was significantly higher than that of the control group (78.72%, 37/47), with statistically significant differences (P<0.05). CONCLUSIONS:The efficacy of traditional Chinese medicine for gastric tube injection and retention enema combined with octreotide in treatment of LBO is remarkable, which can quickly relieve clinical symptoms, shorten therapeutic time and improve therapeutic effect, worthy of recommendation.%目的:探讨中药经胃管注入及保留灌肠联合奥曲肽治疗大肠梗阻的临床疗效.方法:选择2014年1月-2016年12月抚州市东乡区中医院收治的大肠梗阻患者94例,以随机数字表法分为对照组和观察组,每组47例.对照组患者给予奥曲肽治疗,观察组在对照组基础上联合中药经胃管注入及保留灌肠治疗,比较两组患者的治疗效果.结果:观察组患者平均症状完全消失时间、平均肠鸣音恢复时间、平均肛门排气时间及平均住院时间分别为(5.07±1.91)、(2.61±0.99)、(2.88±1.29)及(10.15±3.20) d,分别明显短于对照组的(6.90±1.73)、(3.87±1.25)、(3.74±1.36)及(12.83±5.46) d,差异均有统计学意义(P<0.05);观察组患者的总有效率为95.74%(45/47),明显高于对照组的78.72%(37/47),差异有统计学意义(P<0.05).结论:中药经胃管注入及保留灌肠联合奥曲肽治疗大肠梗阻,可快速缓解患者的临床症状、缩短治疗时间、提高治疗效果,值得推荐.

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