目的:了解河源市中医院(以下简称"我院")骨科Ⅰ类切口手术围术期抗菌药物的预防性应用情况,为进一步加强抗菌药物临床合理应用和规范管理提供参考.方法:选取2016年我院骨科Ⅰ类切口手术出院病例1 660例,对其围术期预防性应用抗菌药物情况进行回顾性调查与分析.结果:1 660例骨科Ⅰ类切口手术患者中,1 011例预防性使用抗菌药物,抗菌药物预防性使用率为60.90%.1 011例预防性用药患者中,不合理用药796例(占78.73%);预防性使用的抗菌药物主要为五水头孢唑林、头孢孟多、头孢替安;术前0.5~1.0 h预防性给药率为98.21%(993例);预防性用药疗程≤24 h者231例(占22.85%),>48 h者460例(占45.49%).结论:我院骨科Ⅰ类切口手术围术期预防性应用抗菌药物存在不合理现象,主要包括抗菌药物品种选择不合理、用药疗程过长等,有待于进一步加强管理,促进抗菌药物的合理应用.%OBJECTIVE:To investigate the preventive application of antibiotics on type Ⅰ incision of orthopedics during perioperative period in Heyuan Hospital of Traditional Chinese Medicine (hereinafter referred to as "our hospital"), so as to provide references for further reinforcement of rational application and standard management of antibiotics. METHODS:1 660 cases of type Ⅰ incision of orthopedics discharged from our hospital in 2016 were selected, the preventive application of antibiotics during perioperative period was retrospectively investigated and analyzed. RESULTS:Of 1 660 patients of type Ⅰ incision of orthopedics, 1 011 cases received preventive application of antibiotics, accounted for 60.90%. Of 1 011 cases of preventive application, 796 patients received irrational drug application, accounted for 78.73%; antibiotics for preventive application mainly included cefazolin sodium pentahydrate for injection, cefamandole and cefotiam; 98.21% (993 cases) of preventive application were 0.5-1.0 h before operation; courses of treatment of 231 cases (accounted for 22.85%) were ≤24 h, 460 cases (45.49%) were >48 h. CONCLUSIONS:There is irrational preventive application of antibiotics existing in type Ⅰ incision of orthopedics during perioperative period in our hospital, mainly included inappropriate choice of antibiotics, overlong courses of treatment and so on, which needs further supervision, so as to promote rational application of antibiotics.
展开▼
