目的:探讨前列地尔、长春西汀联合丹参注射液治疗脑梗死的临床疗效.方法:选取2014年4月—2017年5月广东同江医院收治的脑梗死患者210例进行回顾性研究,根据治疗方法的不同,将其分为观察组110例和对照组100例.对照组患者采用长春西汀联合丹参注射液治疗,观察组患者在对照组的基础上加用前列地尔治疗.观察两组患者的临床疗效、相关实验室指标及不良反应发生情况.结果:观察组患者的总有效率为86.36％(95/110),明显高于对照组的72.00％(72/100),差异有统计学意义(P0.05).结论:前列地尔、长春西汀联合丹参注射液治疗脑梗死的疗效显著,可明显降低患者血清vWF、NSE、s100β及CRP水平,改善认知功能.%OBJECTIVE:To probe into the efficacy of alprostadil and vinpocetine combined with Danshen injection in treatment of cerebral infarction .METHODS:210 patients with cerebral infarction admitted into Guangdong Tongjiang Hospital from Apr .2014 to May 2017 were selected and retrospectively analyzed , patients were divided into observation group (110 cases) and control group (100 cases) according to different therapies .The control group was treated with vinpocetine combined with Danshen injection , while the observation group was treated with alprostadil based on the control group .Clinical efficacy , various indices and incidences of adverse drug reactions of two groups were observed . RESULTS:The total effective rate of observation group ( 86.36％, 95/110 ) was significantly higher than that of the control group (72.00％, 72/100), with statistically significant difference (P0.05 ) .CONCLUSIONS: The efficacy of alprostadil and vinpocetine combined with Danshen injection in treatment of cerebral infarction is remarkable , which can significantly reduce vWF , NSE,s100βand CRP levels , and improve patients ' cognitive function .
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