OBJECTIVE:To probe into the clinical effects of oxytocin nasal spray in treatment of postpartum hemorrhage and prolactin .METHODS: 98 cases with spontaneous labor or cesarean section admitted into Yidu Municipal the First People's Hospital were selected to be divided into observation group and control group via the random number table.As for the 48 cases in control, the baby sucking was encouraged before 3 days, 6 times/d;while the 50 cases in observation group were given the oxytocin nasal spray on the basis of the control group .The amount of postpartum hemorrhage and milk in two group of patients were compared .RRESULTS:The 24h postpartum hemorrhage in observation group was (184.90 ±20.60) ml while in control group was (278.90 ±24.80) ml, the difference was statistically significant ( P<0.05 ) .In observation group , there were 39 cases of postpartum milk sufficient(78.00%), 9 cases of insufficient milk (18.00%), and 2 cases of no milk (4.00%); while in control group were respectively 28 cases ( 58.33%) , 15 cases ( 31.25%) and 5 cases ( 10.42%) , with statistically significant difference ( P<0.05 ) . CONCLUSIONS: Oxytocin nasal spray can effectively reduce the amount of postpartum hemorrhage , promote the lactation yield.It is an effective hemostasis and prolactin drug and worthy of clinical promotion and application .%目的：探讨缩宫素鼻喷剂在产妇产后止血和催乳中的效果。方法：选取宜都市第一人民医院自然分娩或剖宫产的产妇98例作为研究对象，按随机数字表法分为观察组和对照组。对照组48例产妇前3 d鼓励婴儿吸吮，1日6次；观察组50例产妇在对照组处理措施的基础上给予缩宫素鼻喷剂喷鼻，观察2组产妇24 h出血量及奶汁分泌情况。结果：观察组产妇产后24 h出血量为（184.90±20.60） ml，对照组为（278.90±24.80）ml，2组的差异有统计学意义（P ＜0.05）；观察组产妇产后奶汁充足39例（78.00％），奶汁不足9例（18.00％），无奶汁2例（4.00％），对照组产妇产后奶汁充足28例（58.33％），奶汁不足15例（31.25％），无奶汁5例（10.42％），2组的差异有统计学意义（P＜0.05）。结论：缩宫素鼻喷剂可以显著减少产妇产后出血量，促进产妇泌乳量的增加，为有效的止血和催乳药物，值得临床推广。
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