首页> 中文期刊> 《中国医院用药评价与分析》 >小儿氨酚黄那敏颗粒联合利巴韦林气雾剂治疗急性上呼吸道感染的疗效观察

小儿氨酚黄那敏颗粒联合利巴韦林气雾剂治疗急性上呼吸道感染的疗效观察

         

摘要

目的:探讨小儿氨酚黄那敏颗粒联合利巴韦林气雾剂治疗急性上呼吸道感染的疗效。方法:选取2014年2月—2015年2月收治的130例急性上呼吸道感染患儿,运用双色球随机分组法分为观察组和对照组各65例。对照组患儿给予小儿氨酚黄那敏颗粒,观察组在对照组治疗的基础上应用利巴韦林气雾剂,观察2组患儿的疗效、临床症状缓解时间及不良反应发生情况。结果:观察组患儿的总有效率为95.38%(62/65),高于对照组的76.92%(50/65),差异有统计学意义(P<0.05);观察组患者临床症状缓解时间均较对照组明显缩短,差异有统计学意义( P<0.05);2组患儿均未见明显不良反应。结论:氨酚黄那敏颗粒联合利巴韦林气雾剂治疗小儿急性上呼吸道感染效果较好,可明显缓解临床症状,且不良反应少,值得临床推广。%OBJECTIVE:To probe into the efficacy of pediatric paracetamol combined with ribavirin aerosol in treatment of acute upper respiratory tract infection .METHODS: 130 patients with acute upper respiratory tract infection admitted from Feb .2014 to Feb.2015 were selected to be divided into observation group and control group via the two color random grouping method , with 65 cases in each .The control group were given pediatric paracetamol , while the observation group additionally received ribavirin aerosol based on the control group ;the efficacy , relief time of clinical symptoms and adverse drug reactions in two groups were observed .RESULTS: The total effective rate of observation group was 95.38%( 62/65 ) , higher than that of control group 76.92%( 50/65 ) , with statistically significant difference(P<0.05).The relief time of clinical symptoms in observation group significantly shorter than that of control group , with statistically significant difference ( P <0.05 ) .There were no obvious adverse reactions occurred in two groups .CONCLUSIONS: The effects of pediatric paracetamol combined with ribavirin aerosol in treatment of acute upper respiratory tract infection is remarkable , with few adverse drug reactions .It is worthy of clinical application and promotion .

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