目的：了解中山市人民医院（以下简称“我院”）急诊抗菌药物的使用情况，为合理使用抗菌药物提供参考。方法：随机抽取我院2015年1—10月急诊处方4000张，统计抗菌药物使用率、给药途径、抗菌药物的联合应用、各类抗菌药物的使用情况等，并对不合理用药进行分析。结果：4000张急诊处方中，抗菌药物使用率为34.50％（1380张／4000张）；以静脉滴注给药和单一用药为主，各占抗菌药物处方数的83.19％（1148张／1380张）和82.03％（1132张／1380张）；涉及11类抗菌药物，使用率较高的为头孢菌素类、林可霉素类和氟喹诺酮类，分别为51.57％（852例次／1652例次、19.13％（316例次／1652例次）和9.20％（152例次／1652例次）；抗菌药物不合理使用率为18.84％（260张／1380张）。结论：我院急诊抗菌药物的使用基本合理，但也存在部分不合理用药情况，临床医师需加强对抗菌药物合理应用知识的学习，药师应严格审方、及时反馈，共同促进合理用药，防止抗菌药物的滥用。%OBJECTIVE:To investigate the application status of antibiotics in emergency department in Zhongshan People's Hospital ( hereinafter referred to as “our hospital”) , so as to provide reference for the rational application of antibiotics.METHODS: 4 000 emergency prescriptions in our hospital from Jan .to Oct.2015 were randomly selected , the application data were statistically collected in terms of application rate of antibiotics , route of administration , drug combination of antibiotics and application status of different kinds of antibiotics , etc..And the irrational drug use was analyzed .RESULTS: Of the 4 000 prescriptions, the application rate of antibiotics was 34.50%(1 380/4 000 prescriptions );and intravenous infusion and single administration took the lead , respectively accounting for 83.19%( 1 148/1 380 prescriptions ) and 82.03%( 1 132/1 380 prescriptions ) .11 categories of antibiotics were involved , the top three drugs were cephalosporins , lincomycins and quinolones , respectively accounting for 51.57%( 852/1 652 cases ) , 19.13%( 316/1 652 cases ) and 9.20%( 152/1 652 cases ) .The irrational rate of antibiotics was 18.84%( 260/1 380 prescriptions ) .CONCLUSIONS: The application of emergency antibiotics in our hospital is basically rational , but there are also some irrational phenomenon .Therefore , the clinicians need to strengthen the study of the rational application of antibiotics , and the pharmacists should strictly check and timely feedback the irrational prescriptions , so as to jointly promote the rational application of drugs and prevent the abusing of antibiotics .
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