OBJECTIVE:To probe into the efficacy of cefoperazone sulbactam sodium combined with nursing in treatment of critically ill patients in intensive care unit ( ICU ) .METHDS: 120 critically ill patients admitted into Armed Police Corps of Zhejiang Jiaxing Hospital from Jul .2015 to Jul.2016 were selected to be divided into observation group and control group via the random number table , with 60 cases in each .Two group of patients were given corresponding nursing measures , based on which , the observation group were treated with cefoperazone sulbactam sodium injections , while the control group received levofloxacin injections; the treatment effects of two groups were observed .RESULTS: The total effective rate of pulmonary infection therapy in observation group was 94.29%(33/35), significantly higher than that in control group [66.67%(22/33)], with statistically significant difference ( P <0.05 ) .The total effective rate of intracranial infection of acinetobacter baumannii , pseudomonas aeruginosa infection and escherchia coli infection in observation group were significantly higher than those in control group, with statistically significant difference ( P<0.05) .CONCLUSIONS:Cefoperazone sulbactam sodium combined with nursing can effectively improve the treatment effects for critically ill patients in ICU .%目的：探讨头孢哌酮舒巴坦钠联合护理对重症监护病房（ intensive care unit ，ICU）危重患者的疗效。方法：选择武警浙江总队嘉兴医院ICU于2015年7月—2016年7月收治的危重患者120例作为研究对象，按随机数字表法分为观察组和对照组，每组各60例。2组患者均给予相应的护理，在此基础上，观察组患者给予头孢哌酮舒巴坦钠注射液，对照组患者给予左氧氟沙星注射液，观察2组患者的治疗效果。结果：观察组患者肺部感染治疗总有效率为94.29％（33／35），明显高于对照组的66.67％（22／33），差异有统计学意义（P＜0.05）。观察组患者颅内鲍曼不动杆菌感染、铜绿假单胞菌感染以及大肠埃希菌感染的治疗总有效率均显著高于对照组，差异均有统计学意义（ P＜0.05）。结论：ICU危重患者在应用头孢哌酮舒巴坦钠治疗的基础上，加强护理，可显著提高治疗效果。
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