目的：探讨不同药物治疗方案对神经性皮炎的效果与经济学评价。方法：将180例神经性皮炎患者以随机数字表法分为A、B、C组（分别为60、58、62例），分别给予外用糖皮质激素长疗程间歇疗法、降阶梯疗法、常规疗法，观察3组患者临床疗效及安全性。运用成本－效果分析法，对3种治疗方案进行药物经济学评价。结果：3种治疗方案的总成本依次为147．0、212．1、198．4元，总有效率分别为98．33％、94．83％、87．10％，3种方案的成本－效果比分别是1．49、2．24、2．28。结论：A组方案为较佳治疗方案。%OBJECTIVE:To evaluate the therapeutic and pharmacoeconomic efficacy of different therapeutic regimens for neurodermatitis.METHODS: A total of 180 patients with neurodermatitis were randomly assigned to Group A(n=60), B(n=58) and C(n=62) treated with glucocorticoid by long course intermittent treatment, step-down treatment and routine treatment. The efficacy and safety in the three groups were recorded and the pharmacoeconomic efficacy of the three groups was evaluated using cost-effectiveness analysis.RESULTS: The total treatment cost in the three groups were 147.0 Yuan, 212.1 Yuan and 198.4 Yuan, respectively; with total effective rates of 98.33%, 94.83% and 87.1%, respectively and cost-effectiveness ratio of 1.49, 2.24 and 2.28, respectively.CONCLUSIONS:The therapeutic regimen for Group A was the optimal one.
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