OBJECTIVE:To investigate the regulations and characteristics of the adverse drug reaction( ADR) in the Second People's Hospital of Anhui Province ( hereinafter referred to as "our hospital") , and to provide reference for the reduction of the occurrence of ADR. METHODS:Retrospective investigation was adopted, a total of 172 cases of ADR reports collected in our hospital from Jan. 2013 to Dec. 2014 were statistically analyzed. RESULTS:Of the total 172 cases, 93 cases were male, 79 cases were female. There were 80 cases of senile patients aged above 60 years old, accounting for 46. 51%;there were 160 cases of ADR induced by intravenous dripping, accounting for 93. 02%;most ADR were induced by antibiotics drugs, accounting for 26. 16%; the most common clinical manifestations were the damage of skin and its appendants, totally with 56 cases, accounting for 32. 56%. CONCLUSIONS:The clinic should attach more importance to ADR monitoring and report, regulate the rational use of drugs so as to reduce the incidence of ADR.%目的:了解安徽省第二人民医院(以下简称"我院")药品不良反应( adverse drug reaction,ADR)发生的特点与规律,为减少ADR的发生提供参考. 方法:采用回顾性调查方法,对我院2013年1月-2014年12月上报的172例ADR报告进行分析. 结果:172例ADR中,男女患者分别为93、79例;≥60岁患者80例(占46. 51%);静脉给药引发的ADR为160例(占93. 02%);抗感染药引发的ADR为45例(26. 16%);ADR的临床表现主要为皮肤及其附件损害,共56例(32. 56%). 结论:临床应重视ADR的监测与上报工作,规范药品的合理使用,减少ADR的发生.
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