OBJECTIVE:To investigate the incidence of adverse drug reaction ( ADR) in Ankang Central Hospital ( hereinafter referred to as “our hospital”) , and to provide reference for the promotion of clinical rational use of drug . METHODS:Retrospective analysis was adopted , 190 cases of ADR that collected in our hospital during 2012-2015 were analyzed statistically in terms of patients'gender and age , drug types and route of administration etc .RESULTS:Of the 190 ADR cases, males were 116 cases and females were 74 cases, the male/female ratio was 1.6∶1.0;46 cases(24.21%)aged >60 years;127 cases(66.84%)were induced by intravenous injection;40 cases(26.32%) were induced by oral drugs;62 cases ( 31.79% of the total 195 cases ) were induced by the anti-infectious agents , which dominated the first place of ADR incidence; the clinical manifestation of ADR manifested as skin and its accessories damage (85 cases, 33.33% of the total 255 cases).CONCLUSIONS: It is important to strengthen ADR monitoring, promote the rational and standard drug use in our hospital , so as to avoid or reduce the incidence of ADR to ensure safety in drug use .%目的：了解安康市中心医院（以下简称“我院”）药品不良反应（ adverse drug reaction ，ADR）的发生情况，为临床合理用药提供参考。方法：采用回顾性分析方法，对2012—2015年我院收集的190例ADR报告中患者性别、年龄及使用药品种类、给药途径等方面进行统计分析。结果：190例ADR中，男性116例，女性74例，男女之比为1.6∶1.0；＞60岁患者46例（占24.21％）；静脉给药引发ADR 127例（占66.84％），口服给药引发ADR 40例（占26.32％）；抗感染药引发ADR 62例次（占合计195例次的31.79％），居首位；ADR的临床表现主要为皮肤及其附件损害（85例次，占合计255例次的33.33％）。结论：应加强医院ADR监测工作，合理、规范用药，避免或减少ADR发生，保证用药安全。
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