目的：了解北京市丰盛中医骨伤专科医院（以下简称“我院”）药品不良反应（ adverse drug reaction ，ADR）发生的规律、特点及相关因素，为临床合理用药提供参考。方法：采用回顾性方法，对我院2012—2014年上报的93例ADR报告进行统计、分析。结果：93例ADR报告中，患者年龄以60岁以上为主；女性比男性发生ADR的比例高；给药途径以静脉给药方式居多；抗感染药所占比例最高，报告例数为31例（占33.30％），中成药排第2位，报告例数为26例（27.90％）；临床表现以皮肤及其附件最常见，有36例，占38.71％。结论：ADR的发生有多方面因素，应加强ADR的报告与监测，以促进临床合理用药，减少ADR的发生。%OBJECTIVE:To investigate the regularity , characteristics and related factors of adverse drug reactions ( ADR ) in Beijing Fengsheng Special Hospital of Traditional Medical Traumatology and Orthopaedics ( hereinafter referred to as “our hospital”) , so as to provide reference for the clinical rational drug use .METHODS:93 cases of ADR reports reported by our hospital during 2012-2014 were statistically analyzed with the retrospective method . RESULTS:Of the 93 cases, ADR was more often seen in the patients aged over 60 years old and the proportion of female was more than male in ADR .The route of administration was mainly focus on intravenous administration .Anti-infective drugs took up the highest proportion , which caused 31 cases of ADR ( 33.30%); followed by TCM with 26 cases of ADR ( 27.90%) .Skin and its accessories damage were the most common clinical manifestations with 36 cases , accounting for 38.71%.CONCLUSIONS:The occurrence of ADR is associated with a variety of factors .Great importance should be attached to ADR reporting and monitoring to promote the clinical rational drug use , so as to reduce the occurrence of ADR .
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