OBJECTIVE:To probe into the clinical efficacy and safety of Sanjin tablets combined with Norfloxacin tablets in treatment of urinary tract infection .METHODS: 84 cases with urinary tract infection admitted into the hospital from Aug.2010 to Jun.2014 were selected as the research objects , who were divided into observation group and control group , with 42 cases in each group .The observation group were treated with Sanjin tablets combined with norfloxacin tablets while the control group only received orally Norfloxacin tablets .The time of symptom relief , the clinical efficacy and adverse reactions of the two groups were compared .RESULTS:The time of frequent micturition , urgency of urination, dysuria, abdominal bulge, fever, hematuria and the time of pain relief in kidney in the observation group were respectively ( 5.10 ±1.32 ) d, ( 5.77 ±2.31 ) d, ( 2.66 ±1.34 ) d, ( 4.69 ±2.16 ) d, (3.21 ±1.51) d, (3.67 +1.51) d and (3.02 +1.61) d, which were significantly lower than those in the control group(7.87 ±1.51) d,(9.84 ±2.64) d,(4.21 ±0.58) d,(5.83 ±2.61) d,(4.82 ±1.64) d,(6.86 ±1.64) d and (6.58 ±1.94) d, and the difference between groups was statistically significant (P0.05).CONCLUSIONS: Sanjin tablets combined with Norfloxacin tablets in treatment of urinary tract infection has a significant efficacy , which can shorten the time of symptoms with safe and reliable effect; and it is of high value in clinical application .%目的：探讨三金片联合诺氟沙星片治疗尿路感染的临床疗效与安全性。方法：选择2010年8月—2014年6月收治的84例尿路感染患者为研究对象，按随机数字表法分为观察组与对照组各42例，观察组患者采取三金片联合诺氟沙星片治疗，对照组仅口服诺氟沙星片治疗，比较2组患者各症状缓解时间、临床疗效及不良反应。结果：观察组患者尿频、尿急、尿痛、小腹坠胀、发热、血尿、肾区痛缓解时间为（5.10±1.32）、（5.77±2.31）、（2.66±1.34）、（4.69±2.16）、（3.21±1.51）、（3.67±1.51）、（3.02±1.61）d，均显著低于对照组的（7.87±1.51）、（9.84±2.64）、（4.21±0.58）、（5.83±2.61）、（4.82±1.64）、（6.86±1.64）、（6.58±1.94） d，2组的差异有统计学意义（P＜0.05）；观察组患者总有效率为97.62％（41／42），明显优于对照组的85.71％（36／42），差异有统计学意义（P＜0.05）；观察组患者不良反应发生率为7.14％（3／42），对照组为9.52％（4／42），2组的差异无统计学意义（χ2＝0.156，P＞0.05）。结论：三金片联合诺氟沙星片治疗尿路感染效果显著，可缩短症状缓解时间，且安全、可靠，具有较高的临床应用价值。
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