OBJECTIVE:To evaluate the application of antibiotics in the outpatient and emergency pharmacy of the Fifth People's Hospital of Shanghai , Fudan University ( hereinafter referred to as “our hospital”) . METHODS:Retrospective analysis was conducted on the application of antibiotics in the outpatient and emergency pharmacy during 2012-2014 in respect of the consumption sum and DDDs and DDC , etc.RESULTS: As for the consumption sum , the proportion of antibiotics in the total medicines were stable yearly; cephalosporins and macrolides took the lead of the consumption sum list in each year;azithromycin lactobionate dominated the first place during the three years .Cefuroxime axetil , Levofloxacin and Azithromycin tablets ranked the top three in terms of DDDs .CONCLUSIONS:The application of antibiotics in outpatient and emergency pharmacy of our hospital is basically rational .But certain antibiotics have the trend of abuse .It is necessary to further strengthen the supervision so as to promote rational use of antibiotics .%目的：评价复旦大学附属上海市第五人民医院（以下简称“我院”）门、急诊药房抗菌药物的应用情况。方法：对我院2012—2014年门、急诊药房抗菌药物的销售金额、用药频度（ defined daily dose ，DDDs）、日均费用等进行回顾性分析。结果：2012—2014年我院门、急诊患者抗菌药物销售金额占药品总销售金额的比例保持稳定；头孢菌素类、大环内酯类药物的销售金额排序各年度均居前列；乳糖酸阿奇霉素的销售金额3年来均位居首位；而DDDs排列居前3位的为头孢呋辛酯片、左氧氟沙星片和阿奇霉素片。结论：我院门、急诊药房抗菌药物应用基本合理，但个别药物有滥用的趋势，应进一步加强监管，促进抗菌药物的合理应用。
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