OBJECTIVE:To evaluate the antibiotic use in the inpatients of Sanming Youxi County Hospital so as to provide reference for clini-cal rational use and effective management of antibiotics. METHODS:The antibiotic prescriptions in this hospital from July 2012 to September 2013 were retrospectively collected. With defined daily dose as unit,the antibiotic use density (AUD) of different categories/kinds of antibiotics were computed and the results were analyzed. RESULTS:The AUD in the inpatients of this hospital [60-75 DDDs/(100 persons per day)] was higher than that specified by the Ministry of Health. Third-generation cephalosporins,first generation cephalosporins,quinolones and cephamycins still ranked among the top 4 in term of AUD among different antibiotics. CONCLUSIONS:The irrational antibiotic use phenomena including overdose and excessively high grade in drug use level still existed in our hospital,thus intervention measures on which remains to be intensified.%目的：评价专项整治活动后尤溪县医院住院患者抗菌药物的使用情况，为临床合理用药和有效管理提供参考。方法：回顾性收集该院2012年7月至2013年9月所有抗菌药物处方，以限定日剂量为单位，计算各种抗菌药物和各类别抗菌药物的使用强度（AUD），并进行分析。结果：该院住院患者抗菌药物的AUD在60～75 DDDs/（100人·d）之间，高于原卫生部规定的标准。其中，第三代头孢菌素、第一代头孢菌素、喹诺酮类和头霉素类分别居各类别品种抗菌药物AUD的前4位。结论：该院仍存在抗菌药物用药过度、档次过高等问题，需继续加大干预力度。
展开▼
