首页> 中文期刊> 《中国医院用药评价与分析》 >临床药师参与1例药品过敏并发感染性休克的案例分析

临床药师参与1例药品过敏并发感染性休克的案例分析

         

摘要

OBJECTIVE:To explore the approaches for clinical pharmacists to judge and solve adverse drug events. METH-ODS:Based on the drug composition and patient’s specific state,the clinical pharmacist judged and analyzed one typical medical dispute case of suspected Shuganning-induced anaphylactic shock complicating septic shock followed by death. RESULTS:The pa-tient was confirmed as having septic shock yet without Shuganning-induced anaphylactic shock and given positive anti-infection ther-apy using cefoselis and anti-shock therapy using hetastarch,norepinephrine and dopamine,etc. Bacterial culture and sensitivity test results confirmed that the pharmacist’s judgment on the direction of treatment and the choice of antibiotic therapy were correct. CONCLUSIONS:Clinical pharmacists should strengthen their ability in judgment and treatment of patient with adverse drug events and help clinicians to solve practical problems based on patients’specific state and clinical data.%目的:探讨临床药师判断与解决药品不良事件的方法。方法:临床药师结合药品的组方成分和患者的具体情况,对1例疑似舒肝宁引发过敏休克并发感染性休克、继发死亡的医疗纠纷典型案例进行判断和分析。结果:排除舒肝宁的过敏性休克,明确患者为感染性休克。给予头孢噻利积极抗感染治疗,给予羟乙基淀粉、去甲肾上腺素、多巴胺等抗休克治疗。细菌培养和药敏试验结果证实药师在治疗方向及抗菌药的选择上判断正确。结论:临床药师应在实践中强化药品不良事件的判断与救治,结合患者的具体情况和临床数据,协助医师解决临床实际问题。

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