群体感应是微生物调控群体行为的重要方式，基于LuxS的群体感应系统广泛存在于各种属细菌中。AI一2作为LuxS系统的信号分子，在细胞交流中起到关键作用。LuxS系统在多种乳酸菌共同作用完成发酵任务以及某些乳酸菌行使益生功能中发挥了重要作用。文中综述了AI一2的合成途径、转导方式并重点阐述LuxS系统对乳酸菌共培养过程中蛋白表达和基因转录的影响。对LuxS系统进行深入研究，必将进一步揭示多种乳酸菌共同发酵以及其完成益生功能的机理，为从分子水平调控乳酸菌的发酵和益生行为提供了可能。%Quorum sensing is an important way for bacteria to control its group behaviors. LuxS-mediated quorum sensing widely exists in many species of bacteria. AI-2 used as autoinducer of LuxS-mediated system plays an impor- tant role in cell to cell communication. LuxS-mediated system makes a significant effect on fermentation process con- trolled by multiple latic acid bacteria （LAB）. This paper reviews the way of AI-2 synthesis and transduction. We will also focus on the changes of protein expression and gene transcription regulated by LuxS-mediated system under the condition of co-culture among LABs. Researching in LuxS-mediated system will further reveal the mechanism of multiple LABs jointly working in fermentation and make it possible to control sourdough LABs＇ group behaviors in the mo- lecular level.
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