研究明日叶对过度训练致大鼠胃肠功能紊乱的作用。建立雄性大鼠过度训练模型，观察过度训练组、补充明日叶组的大鼠肠道主要菌群双歧杆菌、大肠杆菌数量，肠道代谢产物脲酶、β-半乳糖苷酶活性和主要SCFA含量，以及血浆内毒素、组织匀浆SIgA含量的变化。与正常对照组比较，过度训练组双歧杆菌数量及B/E比值显著升高，大肠杆菌数量显著降低；β-半乳糖苷酶活性及主要SCFA乙酸、丁酸含量显著降低，脲酶活性显著升高；组织匀浆SIgA含量显著下降，而血浆内毒素含量显著升高。补充明日叶组各指标与对照组比较均无显著差异。结果表明，明日叶能够从肠道菌群、肠道代谢产物及肠道屏障等几个方面对肠道微生态进行综合调理，促进肠道健康。%The effect of Ashitaba on gastrointestinal disorders induced by overtraining rat was studied. Male overtraining rats were used as research rats. For exercise, overtraining and Ashitaba supplement, the changes in the numbers of Bifidobacterium and E.coli, the activity ofβ-galactosidase and urease, the content of SCFA, SIgA and plasma endotoxin were measured. Compared with normal control group, in overtraining group, the number of Bifidobacterium and the ratio of B/E were significant increased, the number of E.coli was decreased. The activity ofβ-galactosidase and the levels of acetic acid and butyric acid were remarkably lower in over-training group, in contrast, the activity of urease was higher. The content of SIgA of overtraining groupwas no-tably falling, on the contrary, the level of plasma endotoxin was rising. For the study, ashitaba has a good abili-ty to improve intestinal microecology, such as intestinal flora, intestinal metabolites and intestinal barrier, to promote gut health with a comprehensive and integrated effect.
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