采用响应面分析优化有机溶剂提取树莓叶中总黄酮的工艺。在用有机溶剂提取工艺中，紫树莓叶黄酮提取工艺最佳工艺条件：采用乙醇为溶剂、乙醇浓度为57.8%、提取温度62.1℃、提取时间92.7 min、料液比1∶50（g/mL）。对实验优化条件进行验证得到提取率为12.56%。%Organic solvent extraction of raspberry was optimized by using response surface analysis technology of total flavonoids in the leaves. In organic solvent extraction process , purple raspberry leaf flavonoids extraction process optimum technological conditions for using ethanol as solvent, 57.8%ethanol concentration, extraction temperature 62.1 ℃,the extracting time 92.7 min,material liquid than 1 ∶ 50 (g/mL). The experimental optimization conditions were verified, the extraction yield could reach 12.56%under these conditions.
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