首页> 中文期刊> 《基因组蛋白质组与生物信息学报:英文版》 >The Global Landscape of SARS-CoV-2 Genomes,Variants, and Haplotypes in 2019nCoVR

The Global Landscape of SARS-CoV-2 Genomes,Variants, and Haplotypes in 2019nCoVR

         

摘要

On January 22, 2020, China National Center for Bioinformation(CNCB) released the 2019 Novel Coronavirus Resource(2019 nCoVR), an open-access information resource for the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2). 2019 nCoVR features a comprehensive integration of sequence and clinical information for all publicly available SARS-CoV-2 isolates, which are manually curated with value-added annotations and quality evaluated by an automated in-house pipeline. Of particular note, 2019 nCoVR offers systematic analyses to generate a dynamic landscape of SARS-CoV-2 genomic variations at a global scale. It provides all identified variants and their detailed statistics for each virus isolate, and congregates the quality score, functional annotation,and population frequency for each variant. Spatiotemporal change for each variant can be visualized and historical viral haplotype network maps for the course of the outbreak are also generated based on all complete and high-quality genomes available. Moreover, 2019 nCoVR provides a full collection of SARS-CoV-2 relevant literature on the coronavirus disease 2019(COVID-19), including published papers from PubMed as well as preprints from services such as bioRxiv and medRxiv through Europe PMC. Furthermore, by linking with relevant databases in CNCB, 2019 nCoVR offers data submission services for raw sequence reads and assembled genomes, and data sharing with NCBI. Collectively,SARS-CoV-2 is updated daily to collect the latest information on genome sequences, variants, haplotypes, and literature for a timely reflection, making 2019 nCoVR a valuable resource for the global research community. 2019 nCoVR is accessible at https://bigd.big.ac.cn/ncov/.

著录项

获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号