Micro and Nanotechnology for Intracellular Delivery Therapy Protein

Dan Xu; Zhenhua Hu; Jing Su; Fei Wu∗; Weien Yuan∗

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Micro and Nanotechnology for Intracellular Delivery Therapy Protein

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Proteins therapy is of great importance in the treatment of protein deficiency disease. Most human diseases are related to the malfunctioning of one or more proteins. The most effective and direct ap-proach is protein therapy, which delivers the proteins into the target cell to replace the dysfunction protein and maintain the balance of organism. However, clinical application is frequently hampered by various biological barriers to their successful delivery. This review aims to discuss the recent advances about microparticles and nanoparticles fabricated using micro and nanotechnology for intracellular delivery therapy protein and give some suggestions about the promising delivery system.

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《安徽地质》 |2012年第2期|118-123|共6页
作者
Dan Xu; Zhenhua Hu; Jing Su; Fei Wu∗; Weien Yuan∗;
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School of Pharmacy, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Shanghai 200240, China;

School of Pharmacy, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Shanghai 200240, China;

School of Pharmacy, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Shanghai 200240, China;

School of Pharmacy, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Shanghai 200240, China;

School of Pharmacy, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Shanghai 200240, China;

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Micro and Nanotechnology for Intracellular Delivery Therapy Protein

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