目的：研究乳腺腺体腋尾部注射美蓝示踪哨兵淋巴结法及哨兵淋巴结活检（SLNB）的临床应用。方法应用美蓝腋尾部注射法对44例乳腺癌患者行SLNB，随后行乳腺癌改良根治术。结果哨兵淋巴结SLN的检出率为93.2%，准确性为88.2%，敏感性为93.8%，假阴性率为11.8%，SLNB与ALND阳性率比较无统计学差异。结论美蓝腋尾部注射示踪哨兵淋巴结技术可应用于临床，SLNB活检可用于预测腋窝淋巴结转移情况。%Objective The purpose of this paper is to study the clinical application of tracer method for SLN with methylene blue breast glands axillary tail injection and the sentinel lymph node biopsy (SLNB). Methods The method described in this paper is to apply methylene blue breast glands axillary tail injection to 44 breast cancer cases and perform modiifed radical mastectomy successively. Results The result shows that the detection rate of SLN was 93.2%, accuracy was of 88.2%, sensitivity was of 93.8%, and false-negative rate was of 11.8%. There was no statistical difference of positive rate between SLNB and axillary lymph node dissection (ALND). Conclusion This paper concludes that the technology of SLN tracer method with methylene blue breast glands axillary tail injection can be applied in clinic and SLNB can be applied in prognosis of axillary lymph node metastasis (ALNM).
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