目的：研究分析5-氨基酮戊酸光动力对尖锐湿疣患者治疗效果与病灶HPV载量的影响。方法回顾性分析2013年1月1日至2015年2月1日期间我院的50例尖锐湿疣患者的临床资料，并根据治疗措施分为对照组（20例）和试验组（30例）。给予对照组激光治疗去除疣体，在对照的治疗基础上，给予试验组患者5-氨基酮戊酸光动力治疗，观察、比较两组患者的治疗结果和对患者病灶HPV载量的影响。结果试验组的治愈率（93.33%）高于对照组（60.00%），试验组的复发率（6.67%）低于对照组（40.00%），P＜0.05，具有统计学意义；试验组的除疣后3个月*10*5拷贝较除疣后7~10 d*10*6拷贝有下降，P＜0.01，具有显著统计学意义，较对照组变化更明显。结论5-氨基酮戊酸光动力对尖锐湿疣患者治疗效果较好，复发率低，显著降低病灶HPV载量，可考虑于一定范围内推广应用。%Objective To study and analyze the curative effect of 5-aminolevulinic acid photodynamic on patients with Condyloma Acuminatum lesions and inlfuence on HPV load.Methods Retrospective analyzed clinical data of 50 cases of Condyloma Acuminatum patients in our hospital from January 1, 2013 to February 1, 2015, and according to the treatment method,they were divided into the control group (20 cases) and test group (30 cases).Control group received laser treatment of verrucous body, treatment group were given 5-aminolevulinic acid photodynamic therapy based on control group. Observed and compared the curative effect and inlfuence on patients’ HPV load.Results The cure rate of experimental group (93.33%) was higher than control group’s (60%), the recurrence rate of experimental group (6.67%) was lower than control group’s (40%,P<0.05), with statistical signiifcance; Experimental group’s warts of 105 copies after 3 months was lower than 10 d 106 copies of after 7 months,P<0.01, with statistical signiifcance compared with control group.Conclusion 5-aminolevulinic acid photodynamic has good curative effect on Condyloma Acuminatum, it has low recurrence rate and can signiifcantly reduce the lesion of HPV load, which can be considered popularization and applicationin a certain range.
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