目的：探讨创伤失血性休克并发急性肝功能损害的临床特点。方法回顾性分析2012年3月至2014年5月我院收治的创伤失血性休克患者144例，根据患者2周内是否发生急性肝功能损害分为两组。观察组共72例患者，均为发生急性肝功能损害的患者，对照组共72例，均为未发生急性肝功能损害患者。两组患者均给予规范治疗，用统计学方法比较2周内治疗效果。结果观察组患者中肝功能1级者35例（48.61%），2级者23例（31.94%），3级者14例（19.44%），观察组患者休克持续时间＞6 h，重度休克、血氧饱和度＜90%、多脏器功能障碍及死亡发生率均高于对照组，早期积极干预患者比例低于对照组，两组差异有统计学意义（P＜0.05）。结论密切监测创伤失血性休克患者的肝功能，降低肝损伤发生率。%Objective To investigate the clinical features of liver damage in the acute traumatic hemorrhagic shock.Methods 144 cases with trauma patients with hemorrhagic shock selected from March 2012 to May 2014 in our hospital were retrospective analyzed, according to whether the patient two weeks of acute liver damage occurs. They were divided into two groups, there were 72 patients in the observation group, and all the patients with acute liver damage, there were 72 cases in the control group, all the patients acute liver damage did not occur. Two groups of patients were given standard treatment, the treatment of two groups were compared with statistical methods.Results In the observation groups, liver function 1 grade were 35 cases (48.61%), two grade were 23 cases (31.94%), three grade were 14 cases (19.44%), the incidence of the shock duration>6 h, severe shock, blood oxygen saturation<90%, multiple organ dysfunction and death were higher than the control group, the proportion of patients with early, aggressive intervention were lower than the control group, the difference was signiifcant (P<0.05).Conclusion Closely monitored in patients with traumatic hemorrhagic shock liver function, reduce the incidence of liver damage.
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