目的：探讨高危前列腺增生行经尿道前列腺等离子汽化切除术治疗的效果和安全性。方法将高危前列腺增生的130例患者随机分为观察组和对照组，每组各65例，观察组给予经尿道前列腺等离子汽化切除术（TUPKVP）治疗，对照组给予常规的经尿道前列腺电切术（TURP）治疗。观察两组的手术时间、术中出血量、前列腺切除重量，术后随访3个月，观察两组的IPSS评分、QOL评分、Qmax和术后并发症情况。结果两组患者均顺利完成手术治疗。观察组手术时间、术中出血量显著低于对照组，两组比较差异均有统计学意义(P<0.05)；而两组腺体切除量比较差异无统计学意义(P>0.05)。观察组术后IPSS和QOL评分均显著低于对照组，而尿流率显著高于对照组，两组比较差异均有统计学意义(P<0.05)。观察组术后无电切综合征、继发性出血、尿道狭窄、尿失禁等严重并发症发生。结论 TUPKVP临床疗效显著，手术安全性高，是治疗高危前列腺增生安全、有效的方法。%Objective To evaluate the efficacy and safety of transurethral plasmakinetic vaporize resection of prostate (TUPKVP) for treating the patients with high risk prostatic hyperplasia. Methods One hundred and thirty patients with high risk prostatic hyperplasia were randomly divided into observation group and control group, and each group had 65 cases. The observation group was given the TUPKVP surgery, while the control group was given the conventional transurethral resection of the prostate (TURP) surgery. The operation time, blood loss and prostatecto-my weight of the two groups were observed. The patients were followed up for 3 months.The IPSS score, QOL score, Qmax and postoperative complications of the two groups were observed. Results All patients were successfully com-pleted surgery. The operation time and blood loss of the observation group were significantly lower than that of the control group (P<0.05);the prostatectomy weight of the two groups had no significant difference (P>0.05). The post-operative IPSS and QOL score of the observation group were significantly lower than that of the control group, the Qmax was significantly higher than that of the control group, and the difference was significant (all P<0.05). There were no serious complications of transurethral resection syndrome, secondary hemorrhage, urethral stricture and urinary in-continence in the observation group. Conclusion The TUPKVP has significant clinical efficacy and safety. The TUPKVP is an effective and safe method in treatment of the patients with high risk prostatic hyperplasia.
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