目的 比较和评价射频热凝术与胶原酶化学溶解术治疗腰椎间盘突出症的疗效.方法 124例腰椎间盘突出症患者,根据治疗方法不同分为两组,一组64例,采用射频热凝术治疗；另一组60例,采用胶原酶化学溶解术治疗.于术后1周、3个月及6个月随访,根据MacNab疗效评定标准和VAS评分法,对治疗后优良率、有效率和疼痛程度进行比较.结果 比较124例腰椎间盘突出症患者术后不同时间的疗效,术后1周MacNab标准分析结果,射频组优良率明显高于胶原酶组(P＜0.01)；VAS评分后,射频组优于胶原酶组(P＜0.01).但3个月、6个月后优良率及VAS评分比较差异无统计学意义(P＞0.05).结论 射频术和胶原酶化学溶解术均为治疗腰椎间盘突出症的有效疗法.射频热凝术的近期疗效明显优于胶原酶化学溶核术,但远期疗效两组差异无统计学意义.%Objective To compare and evaluate the effect of radiofrequency thermocoagulation (RF) and collagenase chemonucleolysis (CNL) in the treatment of lumbar intervertebral disc herniation. Methods One hundred and twenty-four patients were divided into two groups based on the treatment they received. Group A (n=64) was treated by RF, and group B (n=60) was treated by CNL. The total effective rate and pain degree were assessed according to MacNab criteria and VAS score one week, three and six months after treatment. Results One week after treatment, the excellent and good rate as well as the VAS scores were significantly better in group A than group B (P<0.01). Three months and six months after treatment, the two groups showed no statistically significant difference in the excellent and good rate as well as the VAS scores (P>0.05). Conclusion RF and CNL are both effective approaches for the treatment of lumbar intervertebral disc herniation. The effect of RF is significantly better than that of CNL in short-term, but there is no statistically significant difference between the two groups in long-term effect.
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