首页> 中文期刊> 《黑龙江医药科学》 >半夏泻心颗粒剂改善胃动力的实验研究

半夏泻心颗粒剂改善胃动力的实验研究

         

摘要

本实验以wistar大鼠和昆明种小白鼠为研究对象,观察"半夏泻心颗粒剂"对大鼠体表胃肌电AP值、FP值以及大、小鼠胃排空率指标,用"酚红法"、"体表胃肌电法"实验并同时做了自身用药前后对比,生理盐水对照和吗丁啉治疗对照。结果"半夏泻心颗粒剂"1.8g/kg,0.9g/kg使大鼠体表胃肌电AP值提高37.5%、82.4%(P<0.01),FP值提高43.3%、18.3%。胃排空率,大鼠提高54.2%(P<0.05),54.9%(P<0.05)小鼠胃排空影响明显,与生理盐水组比较,9g/kg组P<0.05,6g/kg组P<0.01,3g/kg组P<0.01,分别与吗丁啉组接近,结果提示"半夏泻心颗粒剂"有改善大鼠体表胃肌电,提高大、小鼠胃排空的作用。%In order to determine the effect of "granulater of Ban xia xie xin (BXXX)" on gastric dynamic, rat gastro-electrogastrography and rats and mouses red phenal gastrexcretion test were done after administration. The result showed that The gastro-myoelectric AP value of rat body surface was increased by 37.5% or 82.4%(P<0.01) with 1.8g/kg or 0.9g/kg of granulater of BXXX, and FP by 43.3% or 18.3%, respectively. Red phenal gastrexcretion test showed that gastrexcretion rate was increased by 54.2%(P<0.05) and by 59.4%(P<0.05) in rats, but in mice, the effective gastrexcretion was observed (P<0.01), indicating that "granulated of BXXX" had effects of gastro-myoelectric improvement of rat body surface and increase in rat and mouse red phenal gastrexcretion rate.

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