The effects of Breviscapin on microcirculation of naifold andhemorrheology were studied in 100 cases of acute cerebral infarction. It was found that the blood and plasma viscosity was decreased and microcirculation of naifold was improved after treatment(P<0.01).It is suggested that Breviscapin may improve the hemorrheology and microcirculation of naifold. Breviscapin is benificial to the prevention and treatment of acute cerebral infarction.%目的：探讨灯盏花素对脑梗死患者血液流变学及甲襞微循环的影响。方法：随机选择急性脑梗死患者100例，入院后立即静滴灯盏花素30mg，每日1次，疗程14d，连用两个疗程。采用自身对照方法，分别观察治疗前、治疗14d、治疗28d的血液流变学及甲襞微循环的各项指标变化。结果：用灯盏花素后全血粘度、血浆粘度、红细胞压积等血液流变学指标均较用药前明显降低(P<0.01)。甲襞微循环的输出支管径、管袢顶内径、流速等均有显著改善(P<0.01)。结论：灯盏花素能显著改善脑梗死患者血液流变学和微循环情况，从而能防止脑梗死的发生及发展。
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