目的:探讨硅胶泪道引流管联合盐酸洛美沙星眼用凝胶治疗泪道阻塞的临床效果.方法:选取2015-02/12我院泪道阻塞患者86例138眼,根据是否用盐酸洛美沙星眼用凝胶分成对照组43例68眼和观察组43例70眼.对照组患者给予单纯硅胶泪道引流治疗,观察组患者在对照组基础上给予盐酸洛美沙星眼用凝胶治疗.观察并比较两组患者临床总有效率、血清超敏C-反应蛋白(hypersensitive C-reactive protein,h-CRP)水平、并发症和复发率情况.结果:观察组患者的鼻泪管阻塞、泪总管阻塞和泪小管阻塞总有效率分别为95.2%、100.0%、96.7%,均高于对照组患者(P0.05);观察组患者术后3、7d时血清h-CRP水平分别为2.40±0.84、1.94±0.84μg/mL,均低于同时间点对照组患者(P0.05).The serum levels of h-CRP in patients in the observation group at 3d and 7d after operation respectively were 2.40±0.84g/mL, 1.94±0.84g/mL, lower than those of control group at the same time (P<0.05).The complication rate of the observation group was 1.4%, which was lower than that of the control group (P<0.05).Follow up for 6-18mo, the recurrence rate was 11.4% in the observation group, which was significantly lower than the control group (P<0.05).CONCLUSION:The combination of silica gel drainage tube and lomefloxacin hydrochloride eye ophthalmic gel in the treatment of obstruction of lacrimal duct has good clinical efficacy, low inflammatory reaction, low complication rate and low recurrence rate.
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