objective To evaluate the effects of sewing rat tail-ligaments (RTL) under bulbar conjunctiva in prevention and treatment ofherpes simplex keratitis (HSK). Methods RTLs were immersed in 75% alcohol for use. The RTL was sewn under bulbar conjunctiva,2mm from the corneosclera limbus for 1 round. Results The follow upranged from 13 months to 12 years. All patients had irritationsymptoms, especially in the active phase. Most of these irritation symptoms gradually diminished or disappeared within half a month. Ittook 4 to 14 months for the RTL to get absorbed by local tissue. Ninety-eight cases in all the 116 patients were followed up for 3 years.The effective rate was 84%. The recurrence was completely controlled (100%) within 2 years. Conclusion This treatment has relativespecific effects for HSK. It is safe especially effective for control of HSK recurrence and worth popularizing.%目的评估球结膜下缝合小鼠尾韧带(PTL)对单纯疱疹角膜炎(HSK)的预防和治疗效果.方法从杀死的小鼠身上取下尾部韧带,浸泡于75%酒精液中.然后,缝入球结膜下,距角巩膜缘2mm,沿角巩膜缘绕缝1周.术后观察13月至12年.结果所有病人都有刺激症状,特别是在活动期.刺激症状多在半月内逐渐减弱或消失最长延续26天.4到1 4月后RTL被局部组织吸收.116位病人中98位术后观察3年,总有效率为84%.在2年内无复发.结论RTL缝合治疗HSK,操作安全,效果显著,值得推广.
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