Objective To investigate the infection status of HBV, HCV, HIV and microspi-ronema pallidum, and to provide theoretic basis for the prevention of intrauterine infection. Methods Enzyme linked immunosorbent assay (ELISA) was applied to measuring HBV marlers (HBsAg, anti-HBs, HBeAg, anti-HBe, and anti-HBc), anti-HCV, anti-HIV and treponema pallidum particle ag-glutination (TPPA) in 3 649 cases of pregnant women. Results The positive rate of HBsAg, anti-HCV and TPPA was 11.13%, 0.11% and 0. 36% respectively. No anti-HIV positive sample was found. Conclusion The result reveals the epidemiologic feature of HBV, HCV, HIV and microspi-ronema pallidum infection in pregnant women in the city, and it suggests that the serologic examina-tion of HBV, HCV, HIV and TPPA before marriage, progestation, duration of pregnancy and antep-artum be essential to early diagnosis and timely treatment, blockage of intrauterine infection as well as of aristogenesis.%目的 了解孕妇乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)、艾滋病毒(HIV)和梅毒感染情况,为建立有效的防治母婴传播措施提供依据.方法 对来本院做围生保健3 649例孕妇,采用ELISA法检测血清5项乙肝标志物(HBsAg、抗-HBs、HBeAg、抗-HBe和抗-HBc)、抗-HCV、抗-HIV和梅毒血清学检测(TPPA).结果 3 649例孕妇中,HBsAg阳性率为11.13%,抗-HCV和TPPA阳性率分别为0.11%和0.36%,未检测出抗-HIV阳性孕妇.结论 揭示了本市孕妇HBV、HCV、HIV和TPPA感染血清流行病学特征,建议青年男女婚前、孕前、孕期、产前应进行HBV、HCV、HIV和TPPA血清学检查,才能及早发现、及早治疗,有效阻断母婴传播,有利于优生优育.
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