Invasive fractional flow reserve(FFR)is now the gold standard for evaluating coronary artery physiological function.FFR derived from coronary CT angiography(FFRCT)is an imaging post-processing technique,which can be used to evaluate lesion-specific ischemia.Evidences have confirmed its high diagnostic accuracy.FFRCThas been rapidly applied to clinical practice from research.How to optimally implement FFRCTin the daily clinical workflow to maximize the benefit to patients attracts widespread concerns.This review presents the physical principles of FFRCT,considerations and interpretation of FFRCTresults to provide guidance for the clinical application of FFRCT.%有创性血流储备分数(FFR)是评价冠状动脉血管生理功能的金标准.FFRCT是基于冠状动脉CT血管成像的影像后处理技术,可用于评估特异性缺血病灶.大量证据支持FFRCT有很高的诊断准确性,该技术正在从实验研究应用到临床人群.如何在日常临床工作中优化FFRCT技术以实现病人利益最大化引起了广泛关注.总结FFRCT的基本原理,对其注意事项和结果解读进行分析,以利于指导FFRCT的临床应用.
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