microRNA即miRNA,又被称为微小RNA,是一组由18～24个核苷酸长度组成的内源性非编码单链 RNA,研究发现miRNA在包括口腔鳞状细胞癌在内的恶性肿瘤的发生发展中起重要的调控作用.以miRNA为靶标的靶向治疗受到人们的关注,针对miRNA的研究或许能为口腔鳞状细胞癌的治疗找到新的策略.%MicroRNA or miRNA, is a group of which endogenous non-single stranded RNA composed of 18-24 nucleotides in length. miRNA was found in malignant tumors plays an important role in the development of oral squamous cell carcinoma. MiRNAs have been focused on targeted therapy. Studying on miRNA may find a new strategy for the treatment of oral squamous cell carcinoma. The roles of miRNA in the new research progress of OSCC development and the effect of diagnosis and treatment are reviewed.
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