Leucine-rich glioma inactivated 1 (LGil) protein antibody-associated encephalitis is a new type of autoimmune encephalitis, characterized by cognitive impairment and epilepsy and faciobrachial dystonic seizures (FBDS) and intractable hyponatremia. Unlike traditional adenomatous autoimmune encephalitis, it is usually not tumourassociated, and its prognosis is better after immunomodulatory therapy.%富亮氨酸胶质瘤失活(leucine-rich glioma inactivated 1,LGil)蛋白抗体相关脑炎是一种由LGil抗体参与致病的新型自身免疫性脑炎,主要表现为认知障碍、癫痫、面臂肌张力障碍发作(fciobrachial dystonic seizure,FBDS)和顽固性低钠,其中FBDS是其特征性表现.与传统副肿瘤性自身免疫性脑炎不同,该病因其很少伴有肿瘤,经免疫调节治疗后可获得较好的预后.
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