Class Ⅲ malocclusion is one of the most serious craniomaxillofacial malformations. Premaxilla is an important part of the middle face, and its development is critical to maxillofacial morphology. This review will introduce the fetus development of premaxillary-maxillary suture and discuss the relationship between sutural development and Class Ⅲmalocclusion.%骨性Ⅲ类错(牙合)畸形是儿童时期最常见的颅面部畸形之一。前颌骨是中面部的重要结构，它的发育与颌面部形态密切相关。本文就人胎儿前颌缝发育与骨性Ⅲ类错(牙合)畸形儿童的中面部形态特征方面的研究进展作一综述。
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