Objective Evaluation on the effect of single tooth anesthesia(STA) computer-controlled local anes-thetic delivery in tooth extraction to the patients with dental anxiety and cardiovascular disease. Methods Two groups were included. In the experimental group, STA was used, and in the control group, hand injection was performed. Anxiety level before and after injection was evaluated with modified dental anxiety scale. The level of pain during injection was assessed with visual analogue scale by patients after injection. Blood pressure and heart rate were observed before, during and after injection. Results The visual analogue scale value showed a statistical difference between the experimental group and the control group. After injection, 86.11% patients in experimental group were decreased about the incidence rate of scores, which was significiantly superior to control group. No changes in blood pressure and heart rate were found before, during and after injection in the experimental group. The blood pressure increased significantly during injection in the control group. Conclusion STA computer-con-trolled local anesthetic delivery can abate the inject pain and anxiety level, reduce the risk in the operation.% 目的评价单颗牙麻醉（STA）计算机辅助口腔局部麻醉技术应用于伴有牙科焦虑的心血管病患者拔牙时的效果。方法试验分为2组，试验组使用STA进行局部麻醉注射，对照组采用手动注射方式。采用改良牙科焦虑量表评定患者局部麻醉前后的牙科焦虑状况。注射后由患者本人用视觉模拟标尺表评价注射时的疼痛程度。监测麻醉前、中、后患者的血压和心率。结果2组注射时的疼痛评分存在统计学差异。试验组麻醉后有86.11%的患者焦虑评分下降，与对照组相比，两者麻醉前后焦虑变化差异显著。试验组麻醉前、中、后血压和心率变化差异无统计学意义。但是，对照组麻醉中血压明显上升。结论 STA计算机辅助口腔局部麻醉技术能有效减轻注射疼痛，减轻或解除患者的焦虑心理，减少手术风险。
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