Objective To observe and evaluate the relationship between hypertension (EH) complicating hyperuricemia (HUA) and coronary heart disease (CAD).Methods 117 EH patients treated at our hospital from March to December,2016 were selected and were divided into 3 groups by Randomized Controlled Trial (RCT);39 patients with EH were set as a control group,39 with EH and HUA observation group A,and 39 with EH and CAD observation group B.The relationship among the three groups was summarized.Results The levels of TC,GLU,UA,and Cr were significantly higher in the observation group than in the control group (all P ＜ 0.05).The serum uric acid level and incidence of hyperuricemia were significantly higher in the observation group B than in the control group (both P ＜ 0.05).The serum uric acid level and incidence of hyperuricemia increased with the number of vessels with coronary artery disease (both P ＜ 0.05).Conclusions There is a certain relationship between EH complicating HUA and CAD.Hyperuricemia may be related to the development of hypertension and coronary heart disease.Its prognosis also have a certain impact;therefore,significantly controlling the patients'blood pressure and serum uric acid level can effectively prevent and delay the occurrence of coronary heart disease.%目的 观察评价高血压(EH)合并高尿酸血症(HUA)与冠心病(CAD)关系.方法 选取2016年3月至12月本院门诊及住院EH病人117例,随机对照试验(Randomized Controlled Trial,RCT)分为3组:单纯EH病人39例设为对照组,EH伴HUA病人39例设为观察A组,EH伴CAD病人39例设为观察B组;并总结3组之间的关系.结果 观察组TC、GLU、UA、Cr等指标均显著高于对照组(均P＜0.05);观察B组血尿酸浓度、HUA并发率均显著高于对照组(均P＜0.05);随冠状动脉病变血管支数的增加,血尿酸浓度与HUA患病率均明显升高,呈线性趋势(均P＜0.05).结论 EH合并HUA与CAD之间存在着必然的内在联系,HUA可能与EH和CAD的发生发展有一定的相关性,对其预后也产生一定影响,因此,显著控制患者血压、血清尿酸值,才能够有效防治和延缓CAD的发生.
展开▼
