Objective To study the role of parenteral nutrition in early birth weight gain in very low birth weight infants (VLBW).Methods A total of 136 VLBW infants in our hospital from February 2014 to June 2016 were collected and were divided into experimental group and control group.The infants in the control group received routine treatment (including enteral nutrition for tolerant infants);the infants in the experimental group received nutrient solution intravenous infusion therapy based on routine treatment,the nutrient solution contained glucose,protein,and fat,and is based on daily weight and test reports.The weight gain,caloric intake,length of hospital stay,weight at discharge,and survival rate were compared between the two groups.Results The survival rate of the experimental group was 82.61％,while the survival rate of the control group was 70.14％,which was significantly lower than that of the experimental group (x 2=8.374 5,P=0.006 5).The average daily weight gain of the infants in the experimental group was significantly faster than that in the control group (t=44.101 4,P＜0.01),and the average caloric intake was also significantly higher than that in the control group (t=4.473 8,P＜0.01).There was no statistically significant difference in weight between the two groups at discharge (t=0.874 1,P=0.38),but the length of stay in the experimental group was significantly shorter than that in the control group (t=7.401 7,P＜0.01).Conclusion Early intravenous nutrition for VLBW can effectively improve the weight gain,increase the caloric intake,shorten the hospitalization time,and reduce the mortality rate,and has positive significance for the treatment of VLBW infants.%目的 研究静脉营养在极低出生体重儿(VLBW)出生早期体重增长中的作用.方法 收集了2014年2月至2016年6月间在本院住院的VLBW共136例,将患几分为试验组和对照组.予以对照组患儿常规治疗(包括能耐受患儿肠道内营养),试验组患儿常规治疗基础上综合营养液(综合营养液包含葡萄糖、蛋白质和脂肪,根据患儿每日体重及检验报告进行调配)静脉输入治疗.比较两组患儿治疗期间的体重增长情况、热量摄入情况、住院天数、出院时体重及存活率.结果 试验组患儿存活率为82.61％,而对照组患儿的存活率为70.15％,明显低于试验组(x2=8.374 5,P=0.006 5).试验组患儿第1周的体重每日平均增长幅度明显快于对照组(t=44.101 4,P＜0.01),1月内平均热量摄入也显著高于对照组(t=4.473 8,P＜0.01).两组患者出院时的体重比较差异无统计学意义(t=0.874 1,P=0.38),但试验组的住院天数明显短于对照组(t=7.401 7,P＜0.01).结论 予以VLBW早期静脉营养,能够有效提高患儿体重增长幅度,增加热量摄入,缩短住院时间,减少死亡率,对VLBW的治疗有积极意义.
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