Objective To investigate the effect of laparoscopic gastric bypass surgery in the treatment of patients with type 2 diabetes mellitus and low BMI.Methods 50 patients with type 2 diabetes mellitus and low BMI undertaking laparoscopic gastric bypass surgery at our hospital were selected as study objects.The blood lipid,body mass index (BMI),fasting plasma glucose (FPG),meal 2 hours blood glucose (PBG),glycosylated hemoglobin (HbA 1 c),and quality of life were observed in the patients.Results 6 months after laparoscopic gastric bypass surgery,the total cholesterol level was (4.66 ± 0.39) mmol/L,triglyceride level (1.65 ± 0.24) mmol/L,low density lipoprotein level (2.63 ± 0.15) mmol/L,high density lipoprotein level (1.54 ± 0.32) mmol/L,BMI (20.67± 2.01) kg/m2,FPG (5.12 ± 0.31) mmol/L,PBG (5.82 ± 0.65) mmol/L,HbA1C (5.36 ± 0.47)％,physiological function (70.83 ± 4.58),physiological function (61.74 ± 4.35),bodily pain (70.23 ± 4.37),general health (75.46 ±4.28),energy (58.46 ± 4.35),social function (61.81 ± 4.71),emotional function (60.74 ± 4.49),and mental health (60.42 ± 4.82),which were all better than those before treatment in all the patients,with statistical differences (P＜0.05).Conclusions Laparoscopic gastric bypass surgery in the treatment of patients with type 2 diabetes and low BMI has definite clinical efficacy and can significantly improve the patients' indicators and quality of life,so it can be regarded as medication or insulin therapy in patients with type 2 diabetes and worth for clinical application.%目的 探讨腹腔镜胃旁路术治疗低体重指数(BMI)2型糖尿病患者效果.方法 选取本院收治的50例实施腹腔镜胃旁路术治疗的低BMI 2型糖尿病患者为研究对象,观察患者血脂、BMI、空腹血浆葡萄糖(FPG)、餐后 2h 血糖PBG、糖化血红蛋白(HbA1C)及其生活质量.结果 实施腹腔镜胃旁路术后6个月,患者总胆固醇为(4.66±0.39) mmol/L、甘油三酯为(1.65±0.24) mmol/L、低密度脂蛋白为(2.63±0.15) mmol/L、高密度脂蛋白为(1.54±0.32) mmo]/L、BMI为(20.67±2.01) kg/m2、空腹血浆FPG为(5.12±0.31) mmol/L、餐后 2h 血糖PBG为(5.82±0.65) mmol/L、HbA1C为(5.36±0.47)％、生理机能为(70.83±4.58)分、生理职能为(61.74±4.35)分、躯体疼痛为(70.23±4.37)分、一般健康状况为(75.46±4.28)分、精力为(58.46±4.35)分、社会功能为(61.81±4.71)分、情感职能为(60.74±4.49)分、精神健康为(60.42±4.82)分,均优于治疗前,差异有统计学意义,P＜0.05.结论 腹腔镜胃旁路术治疗低BMI 2型糖尿病患者临床疗效确切,能够显著改善患者各项指标及生活质量,不失为药物或胰岛素治疗欠佳的 2型糖尿病患者的治疗手段,值得临床应用.
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